Not all women with irregular periods have PCOS and women with PCOS can have regular periods. As a complex hormonal and metabolic condition, PCOS and its diagnosis can be a tricky process and this is quite a vexation to many women.
Why is PCOS diagnosis tricky?When it comes to PCOS diagnosis, there is certainly a bit of unpredictability for various reasons. First of all, PCOS symptoms are varied. Added to that, not all women experience the same symptoms. Further, many other conditions share the same symptoms as PCOS. So, there is every chance that symptoms can be misread.
Common PCOS symptoms
- Amenorrhea (no menstruation)
- Oligomenorrhea (infrequent menstrual cycles)
- Dysfunctional uterine bleeding
- Anovulation (ovaries not releasing oocyte)
- Multiple ovarian cysts
- Hirsutism (excess facial hair)
- Thinning of scalp hair
- Acanthosis nigricans (Dark pigmentation on skin)
- Insulin resistance
- High triglycerides and low-density cholesterol
Who should get investigated for PCOS?With the complexity involved in the symptoms, PCOS diagnosis and investigation should be done for women who have the following characteristics.
- Chronic anovulation
- Moderate to severe acne
- Adult acne
- Acanthosis nigricans
- Upper body obesity
- Deepening of voice
- Abnormal growth of muscles
- Progressive hair loss
- Increasing hair near upper lip, chin, chest, back, & abdomen (Hirsutism)
- Family or personal history of type 2 diabetes with the above symptoms
PCOS DiagnosisSince there is no specific test for PCOS diagnosis, a combination of certain clinical features is considered as PCOS.
Clinical features of PCOS
- Acanthosis nigricans
- Scalp hair loss
- Infertility (subfertility) or miscarriage in first trimester
Criteria for PCOS DiagnosisSince PCOS manifests in the form of multiple symptoms and each symptom can be caused due to other conditions, there are certain criteria for PCOS diagnosis. The Rotterdam criteria is among the most contemporary set of rules for confirming PCOS diagnosis.
Rotterdam Criteria for diagnosis of PCOS
- Oligoovulation or anovulation
- Hyperandrogenism with male pattern hair loss or clinical Hirsutism and raised levels of FAI or free testosterone (biochemical)
- Observation of polycystic ovaries in ultrasound examination
Diagnostic Tests for PCOS
- Luteal Progesterone level test to determine anovulation
- Total testosterone, free testosterone, Free Androgen index, DHEAS tests for hyperandrogenism
- Ultrasound examination with the presence of polycystic ovaries. The presence of at least 10 antral follicles in each ovary is considered as polycystic ovaries