Capillary leak syndrome is a rare disease that can sometimes occur in senior people with diabetes. It is a condition in which proteins and fluids leak from the capillaries into the surrounding tissues. This condition is characterized by symptoms of fatigue, abdominal pain, nausea, thirst, and flu-like symptoms. When untreated capillary leak syndrome can lead to conditions like extremely low blood pressure, decreased plasma volume in the blood, hypoalbuminemia. Capillary leak syndrome can be systemic, in which there is a massive leak of plasma into the surrounding tissues. This occurs in rare diseases like Clarkson’s disease. Capillary leak syndrome can be due to unknown causes. It can occur due to sepsis, autoimmune diseases, poisoning, hemorrhagic fevers, and others. This condition is diagnosed by physical examination, lab tests, and the presence of symptoms. Capillary leak syndrome has no cure and hence treatment during an episode aims to provide stabilization from symptoms, life support and protection against severe complications. For someone who has recurrent episodes of capillary leak syndrome, prophylactic treatment is prescribed. In people with diabetes, diabetic ketoacidosis is a serious complication that arises due to a severe shortage of insulin. It can arise in both type 1 and type 2 patients. In this condition, the body has insufficient insulin and so it starts to process fats to produce energy. This results in an unusual buildup of acidic ketones, which is harmful. This condition can lead to cardiogenic and non-cardiogenic pulmonary edema. The buildup of fluid in the lungs due to non-cardiogenic factors is due to a kind of capillary leak syndrome. This is a fatal complication that is caused due to the permeability of the capillaries of the lungs.
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