Café au lait spots are spots that appear on the skin. These are flat and can be in dark coffee color in people with dark skin and light in people with fair skin. Though these spots are supposed to be harmless, they might be indicators of an underlying disease. Café au lait in French means coffee with milk and it describes the color of the spots. These spots are generally permanent and are the result of melanocytes that are pigment-making cells. These spots might grow in size and might be indicators of diseases like neurofibromatosis. They are indicators of neurofibromatosis if the spots are more than six in number and their diameter is 1.5 cm or more. Café au lait spots are hyperpigmented lesions on the epidermis of the skin with irregular borders, which might be present right from infancy. Neurofibromatosis is an autoimmune disease and only rarely diabetes and neurofibromatosis occur together. However, when it occurs, it occurs in children and it causes type 1 diabetes. When neurofibromatosis and type 1 diabetes occurs together, it most likely occurs due to the presence of somatostatinomas in the pancreas. The somatostatinomas is caused due to neurofibromatosis, which makes the pancreas ineffective.
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